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In this issue, we dive into the promise of ibogaine to not only cure opioid dependence-but to help solve fundamental mysteries about the nature of addiction. (There's still so much we don't understand about why people get addicted, whether it's to their screens or to alcohol.) We speak to folks with the decrim campaigns about why they think mushroom cultivation is the best way to combat "corporadelics" (yes, that's a thing). And we move beyond individual healing to explore how psychedelics -ayahuasca specifically-might help political conflict.